2026-02-16T19:35:43,546 Created temporary directory: /tmp/pip-ephem-wheel-cache-ip0ob3mn 2026-02-16T19:35:43,547 Created temporary directory: /tmp/pip-build-tracker-_53ere5m 2026-02-16T19:35:43,548 Initialized build tracking at /tmp/pip-build-tracker-_53ere5m 2026-02-16T19:35:43,548 Created build tracker: /tmp/pip-build-tracker-_53ere5m 2026-02-16T19:35:43,549 Entered build tracker: /tmp/pip-build-tracker-_53ere5m 2026-02-16T19:35:43,550 Created temporary directory: /tmp/pip-wheel-1ljsm_9t 2026-02-16T19:35:43,553 DEPRECATION: --no-binary currently disables reading from the cache of locally built wheels. In the future --no-binary will not influence the wheel cache. pip 23.1 will enforce this behaviour change. A possible replacement is to use the --no-cache-dir option. You can use the flag --use-feature=no-binary-enable-wheel-cache to test the upcoming behaviour. Discussion can be found at https://github.com/pypa/pip/issues/11453 2026-02-16T19:35:43,555 Created temporary directory: /tmp/pip-ephem-wheel-cache-5ez1p21z 2026-02-16T19:35:43,577 Looking in indexes: https://pypi.org/simple, https://www.piwheels.org/simple 2026-02-16T19:35:43,581 2 location(s) to search for versions of refua-clinical: 2026-02-16T19:35:43,581 * https://pypi.org/simple/refua-clinical/ 2026-02-16T19:35:43,581 * https://www.piwheels.org/simple/refua-clinical/ 2026-02-16T19:35:43,582 Fetching project page and analyzing links: https://pypi.org/simple/refua-clinical/ 2026-02-16T19:35:43,582 Getting page https://pypi.org/simple/refua-clinical/ 2026-02-16T19:35:43,584 Found index url https://pypi.org/simple 2026-02-16T19:35:43,805 Fetched page https://pypi.org/simple/refua-clinical/ as application/vnd.pypi.simple.v1+json 2026-02-16T19:35:43,807 Skipping link: No binaries permitted for refua-clinical: https://files.pythonhosted.org/packages/d3/09/1099b09fdc5667f97597d2513946ba54b9996ee1a9a8d93672b61f53bc9b/refua_clinical-0.2.0-py3-none-any.whl (from https://pypi.org/simple/refua-clinical/) (requires-python:<3.15,>=3.11) 2026-02-16T19:35:43,808 Found link https://files.pythonhosted.org/packages/bd/53/d8a3c8648b32e3af4e2a4bb64f9d7222a5bd7f6a85c286efd8939b3e9b19/refua_clinical-0.2.0.tar.gz (from https://pypi.org/simple/refua-clinical/) (requires-python:<3.15,>=3.11), version: 0.2.0 2026-02-16T19:35:43,809 Fetching project page and analyzing links: https://www.piwheels.org/simple/refua-clinical/ 2026-02-16T19:35:43,810 Getting page https://www.piwheels.org/simple/refua-clinical/ 2026-02-16T19:35:43,811 Found index url https://www.piwheels.org/simple 2026-02-16T19:35:43,962 Fetched page https://www.piwheels.org/simple/refua-clinical/ as text/html 2026-02-16T19:35:43,964 Skipping link: not a file: https://www.piwheels.org/simple/refua-clinical/ 2026-02-16T19:35:43,964 Skipping link: not a file: https://pypi.org/simple/refua-clinical/ 2026-02-16T19:35:43,985 Given no hashes to check 1 links for project 'refua-clinical': discarding no candidates 2026-02-16T19:35:44,004 Collecting refua-clinical==0.2.0 2026-02-16T19:35:44,007 Created temporary directory: /tmp/pip-unpack-7794avbd 2026-02-16T19:35:44,489 Downloading refua_clinical-0.2.0.tar.gz (51 kB) 2026-02-16T19:35:44,622 Added refua-clinical==0.2.0 from https://files.pythonhosted.org/packages/bd/53/d8a3c8648b32e3af4e2a4bb64f9d7222a5bd7f6a85c286efd8939b3e9b19/refua_clinical-0.2.0.tar.gz to build tracker '/tmp/pip-build-tracker-_53ere5m' 2026-02-16T19:35:44,628 Created temporary directory: /tmp/pip-build-env-lk9uc418 2026-02-16T19:35:44,632 Installing build dependencies: started 2026-02-16T19:35:44,634 Running command pip subprocess to install build dependencies 2026-02-16T19:35:45,756 Using pip 23.0.1 from /usr/lib/python3/dist-packages/pip (python 3.11) 2026-02-16T19:35:46,335 DEPRECATION: --no-binary currently disables reading from the cache of locally built wheels. In the future --no-binary will not influence the wheel cache. pip 23.1 will enforce this behaviour change. A possible replacement is to use the --no-cache-dir option. You can use the flag --use-feature=no-binary-enable-wheel-cache to test the upcoming behaviour. Discussion can be found at https://github.com/pypa/pip/issues/11453 2026-02-16T19:35:46,359 Looking in indexes: https://pypi.org/simple, https://www.piwheels.org/simple 2026-02-16T19:35:48,080 Collecting setuptools>=68 2026-02-16T19:35:48,158 Using cached https://www.piwheels.org/simple/setuptools/setuptools-82.0.0-py3-none-any.whl (1.0 MB) 2026-02-16T19:35:48,428 Collecting wheel 2026-02-16T19:35:48,444 Using cached https://www.piwheels.org/simple/wheel/wheel-0.46.3-py3-none-any.whl (30 kB) 2026-02-16T19:35:48,633 Collecting packaging>=24.0 2026-02-16T19:35:48,650 Using cached https://www.piwheels.org/simple/packaging/packaging-26.0-py3-none-any.whl (74 kB) 2026-02-16T19:35:51,661 Installing collected packages: setuptools, packaging, wheel 2026-02-16T19:35:55,048 Creating /tmp/pip-build-env-lk9uc418/overlay/local/bin 2026-02-16T19:35:55,051 changing mode of /tmp/pip-build-env-lk9uc418/overlay/local/bin/wheel to 755 2026-02-16T19:35:55,072 Successfully installed packaging-26.0 setuptools-82.0.0 wheel-0.46.3 2026-02-16T19:35:55,350 Installing build dependencies: finished with status 'done' 2026-02-16T19:35:55,357 Getting requirements to build wheel: started 2026-02-16T19:35:55,358 Running command Getting requirements to build wheel 2026-02-16T19:35:56,077 running egg_info 2026-02-16T19:35:56,083 writing src/refua_clinical.egg-info/PKG-INFO 2026-02-16T19:35:56,090 writing dependency_links to src/refua_clinical.egg-info/dependency_links.txt 2026-02-16T19:35:56,092 writing entry points to src/refua_clinical.egg-info/entry_points.txt 2026-02-16T19:35:56,096 writing requirements to src/refua_clinical.egg-info/requires.txt 2026-02-16T19:35:56,097 writing top-level names to src/refua_clinical.egg-info/top_level.txt 2026-02-16T19:35:56,117 reading manifest file 'src/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:56,122 reading manifest template 'MANIFEST.in' 2026-02-16T19:35:56,129 adding license file 'LICENSE' 2026-02-16T19:35:56,133 writing manifest file 'src/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:56,229 Getting requirements to build wheel: finished with status 'done' 2026-02-16T19:35:56,233 Created temporary directory: /tmp/pip-modern-metadata-u_l3_bk3 2026-02-16T19:35:56,235 Preparing metadata (pyproject.toml): started 2026-02-16T19:35:56,236 Running command Preparing metadata (pyproject.toml) 2026-02-16T19:35:56,907 running dist_info 2026-02-16T19:35:56,917 creating /tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info 2026-02-16T19:35:56,918 writing /tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/PKG-INFO 2026-02-16T19:35:56,924 writing dependency_links to /tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/dependency_links.txt 2026-02-16T19:35:56,926 writing entry points to /tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/entry_points.txt 2026-02-16T19:35:56,929 writing requirements to /tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/requires.txt 2026-02-16T19:35:56,930 writing top-level names to /tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/top_level.txt 2026-02-16T19:35:56,932 writing manifest file '/tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:56,950 reading manifest file '/tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:56,951 reading manifest template 'MANIFEST.in' 2026-02-16T19:35:56,957 adding license file 'LICENSE' 2026-02-16T19:35:56,961 writing manifest file '/tmp/pip-modern-metadata-u_l3_bk3/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:56,962 creating '/tmp/pip-modern-metadata-u_l3_bk3/refua_clinical-0.2.0.dist-info' 2026-02-16T19:35:57,085 Preparing metadata (pyproject.toml): finished with status 'done' 2026-02-16T19:35:57,090 Source in /tmp/pip-wheel-1ljsm_9t/refua-clinical_e06c20c9f2fd4cde81e60617062acc3e has version 0.2.0, which satisfies requirement refua-clinical==0.2.0 from https://files.pythonhosted.org/packages/bd/53/d8a3c8648b32e3af4e2a4bb64f9d7222a5bd7f6a85c286efd8939b3e9b19/refua_clinical-0.2.0.tar.gz 2026-02-16T19:35:57,091 Removed refua-clinical==0.2.0 from https://files.pythonhosted.org/packages/bd/53/d8a3c8648b32e3af4e2a4bb64f9d7222a5bd7f6a85c286efd8939b3e9b19/refua_clinical-0.2.0.tar.gz from build tracker '/tmp/pip-build-tracker-_53ere5m' 2026-02-16T19:35:57,098 Created temporary directory: /tmp/pip-unpack-q06p2da4 2026-02-16T19:35:57,099 Building wheels for collected packages: refua-clinical 2026-02-16T19:35:57,103 Created temporary directory: /tmp/pip-wheel-3lt6n8no 2026-02-16T19:35:57,104 Destination directory: /tmp/pip-wheel-3lt6n8no 2026-02-16T19:35:57,106 Building wheel for refua-clinical (pyproject.toml): started 2026-02-16T19:35:57,107 Running command Building wheel for refua-clinical (pyproject.toml) 2026-02-16T19:35:57,727 running bdist_wheel 2026-02-16T19:35:57,744 running build 2026-02-16T19:35:57,745 running build_py 2026-02-16T19:35:57,751 creating build/lib/refua_clinical 2026-02-16T19:35:57,753 copying src/refua_clinical/transportability.py -> build/lib/refua_clinical 2026-02-16T19:35:57,755 copying src/refua_clinical/protocol.py -> build/lib/refua_clinical 2026-02-16T19:35:57,757 copying src/refua_clinical/cli.py -> build/lib/refua_clinical 2026-02-16T19:35:57,759 copying src/refua_clinical/models.py -> build/lib/refua_clinical 2026-02-16T19:35:57,762 copying src/refua_clinical/optimization.py -> build/lib/refua_clinical 2026-02-16T19:35:57,764 copying src/refua_clinical/__main__.py -> build/lib/refua_clinical 2026-02-16T19:35:57,765 copying src/refua_clinical/research.py -> build/lib/refua_clinical 2026-02-16T19:35:57,768 copying src/refua_clinical/pkpd.py -> build/lib/refua_clinical 2026-02-16T19:35:57,770 copying src/refua_clinical/integrations.py -> build/lib/refua_clinical 2026-02-16T19:35:57,772 copying src/refua_clinical/virtual_patients.py -> build/lib/refua_clinical 2026-02-16T19:35:57,774 copying src/refua_clinical/__init__.py -> build/lib/refua_clinical 2026-02-16T19:35:57,776 copying src/refua_clinical/voi.py -> build/lib/refua_clinical 2026-02-16T19:35:57,777 copying src/refua_clinical/stopping.py -> build/lib/refua_clinical 2026-02-16T19:35:57,779 copying src/refua_clinical/trial.py -> build/lib/refua_clinical 2026-02-16T19:35:57,782 copying src/refua_clinical/admet_integration.py -> build/lib/refua_clinical 2026-02-16T19:35:57,784 copying src/refua_clinical/explainability.py -> build/lib/refua_clinical 2026-02-16T19:35:57,786 copying src/refua_clinical/estimands.py -> build/lib/refua_clinical 2026-02-16T19:35:57,788 copying src/refua_clinical/io.py -> build/lib/refua_clinical 2026-02-16T19:35:57,790 running egg_info 2026-02-16T19:35:57,800 writing src/refua_clinical.egg-info/PKG-INFO 2026-02-16T19:35:57,805 writing dependency_links to src/refua_clinical.egg-info/dependency_links.txt 2026-02-16T19:35:57,807 writing entry points to src/refua_clinical.egg-info/entry_points.txt 2026-02-16T19:35:57,810 writing requirements to src/refua_clinical.egg-info/requires.txt 2026-02-16T19:35:57,811 writing top-level names to src/refua_clinical.egg-info/top_level.txt 2026-02-16T19:35:57,821 reading manifest file 'src/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:57,825 reading manifest template 'MANIFEST.in' 2026-02-16T19:35:57,831 adding license file 'LICENSE' 2026-02-16T19:35:57,835 writing manifest file 'src/refua_clinical.egg-info/SOURCES.txt' 2026-02-16T19:35:57,838 copying src/refua_clinical/py.typed -> build/lib/refua_clinical 2026-02-16T19:35:57,849 installing to build/bdist.linux-armv7l/wheel 2026-02-16T19:35:57,850 running install 2026-02-16T19:35:57,873 running install_lib 2026-02-16T19:35:57,879 creating build/bdist.linux-armv7l/wheel 2026-02-16T19:35:57,881 creating build/bdist.linux-armv7l/wheel/refua_clinical 2026-02-16T19:35:57,882 copying build/lib/refua_clinical/transportability.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,885 copying build/lib/refua_clinical/protocol.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,887 copying build/lib/refua_clinical/cli.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,890 copying build/lib/refua_clinical/models.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,892 copying build/lib/refua_clinical/optimization.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,894 copying build/lib/refua_clinical/__main__.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,896 copying build/lib/refua_clinical/research.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,898 copying build/lib/refua_clinical/pkpd.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,900 copying build/lib/refua_clinical/integrations.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,902 copying build/lib/refua_clinical/virtual_patients.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,904 copying build/lib/refua_clinical/py.typed -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,906 copying build/lib/refua_clinical/__init__.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,908 copying build/lib/refua_clinical/voi.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,910 copying build/lib/refua_clinical/stopping.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,912 copying build/lib/refua_clinical/trial.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,915 copying build/lib/refua_clinical/admet_integration.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,917 copying build/lib/refua_clinical/explainability.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,920 copying build/lib/refua_clinical/estimands.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,921 copying build/lib/refua_clinical/io.py -> build/bdist.linux-armv7l/wheel/./refua_clinical 2026-02-16T19:35:57,924 running install_egg_info 2026-02-16T19:35:57,928 Copying src/refua_clinical.egg-info to build/bdist.linux-armv7l/wheel/./refua_clinical-0.2.0-py3.11.egg-info 2026-02-16T19:35:57,940 running install_scripts 2026-02-16T19:35:57,953 creating build/bdist.linux-armv7l/wheel/refua_clinical-0.2.0.dist-info/WHEEL 2026-02-16T19:35:57,956 creating '/tmp/pip-wheel-3lt6n8no/.tmp-wny3gow9/refua_clinical-0.2.0-py3-none-any.whl' and adding 'build/bdist.linux-armv7l/wheel' to it 2026-02-16T19:35:57,958 adding 'refua_clinical/__init__.py' 2026-02-16T19:35:57,960 adding 'refua_clinical/__main__.py' 2026-02-16T19:35:57,961 adding 'refua_clinical/admet_integration.py' 2026-02-16T19:35:57,965 adding 'refua_clinical/cli.py' 2026-02-16T19:35:57,966 adding 'refua_clinical/estimands.py' 2026-02-16T19:35:57,970 adding 'refua_clinical/explainability.py' 2026-02-16T19:35:57,971 adding 'refua_clinical/integrations.py' 2026-02-16T19:35:57,974 adding 'refua_clinical/io.py' 2026-02-16T19:35:57,976 adding 'refua_clinical/models.py' 2026-02-16T19:35:57,978 adding 'refua_clinical/optimization.py' 2026-02-16T19:35:57,979 adding 'refua_clinical/pkpd.py' 2026-02-16T19:35:57,981 adding 'refua_clinical/protocol.py' 2026-02-16T19:35:57,983 adding 'refua_clinical/py.typed' 2026-02-16T19:35:57,984 adding 'refua_clinical/research.py' 2026-02-16T19:35:57,986 adding 'refua_clinical/stopping.py' 2026-02-16T19:35:57,987 adding 'refua_clinical/transportability.py' 2026-02-16T19:35:57,990 adding 'refua_clinical/trial.py' 2026-02-16T19:35:57,992 adding 'refua_clinical/virtual_patients.py' 2026-02-16T19:35:57,993 adding 'refua_clinical/voi.py' 2026-02-16T19:35:57,996 adding 'refua_clinical-0.2.0.dist-info/licenses/LICENSE' 2026-02-16T19:35:57,998 adding 'refua_clinical-0.2.0.dist-info/METADATA' 2026-02-16T19:35:57,999 adding 'refua_clinical-0.2.0.dist-info/WHEEL' 2026-02-16T19:35:58,000 adding 'refua_clinical-0.2.0.dist-info/entry_points.txt' 2026-02-16T19:35:58,001 adding 'refua_clinical-0.2.0.dist-info/top_level.txt' 2026-02-16T19:35:58,002 adding 'refua_clinical-0.2.0.dist-info/RECORD' 2026-02-16T19:35:58,004 removing build/bdist.linux-armv7l/wheel 2026-02-16T19:35:58,107 Building wheel for refua-clinical (pyproject.toml): finished with status 'done' 2026-02-16T19:35:58,113 Created wheel for refua-clinical: filename=refua_clinical-0.2.0-py3-none-any.whl size=50286 sha256=403ce34c269264359dc4e7bdc695b91f05d2e0367c62416e0cabc0535937b104 2026-02-16T19:35:58,114 Stored in directory: /tmp/pip-ephem-wheel-cache-5ez1p21z/wheels/04/2d/4a/c5301862ed0cbd842e1fc41ae0e120dfd5147a9ce2ac9ab463 2026-02-16T19:35:58,126 Successfully built refua-clinical 2026-02-16T19:35:58,131 Removed build tracker: '/tmp/pip-build-tracker-_53ere5m'